![]() The bulge can burst and cause internal bleeding in the brain. Learn more about PAD from the American Heart Association and the Vascular Disease Foundation.Ītherosclerosis can cause an aneurysm, which is a bulge in a weakened area of your artery wall. It may also affect the arteries supplying blood to your kidneys or stomach, increasing the risk of organ damage. Pain in the leg is usually the first sign of PAD, but PAD can occur elsewhere in the body. If the arteries in your legs or arms become narrow or blocked, you may develop peripheral arterial disease (PAD), leading to cramping muscular pain while walking or during exercise. A piece of plaque can break off, travel through the arteries to the brain, block blood vessels in the brain and cause a stroke or mini-stroke (TIA). If the arteries in your neck become narrow or blocked, blood flow to the brain can slow down or stop. ![]() Microvascular angina can cause chest pain even when tests don’t show any blockages in the bigger arteries. ![]() If plaque forms in the very small arteries of the heart, it can cause coronary microvascular disease. Coronary artery disease can cause a heart attack. If one or more of the coronary arteries becomes narrowed or blocked, blood flow to the heart can slow down or stop. The heart is a muscle and needs a supply of oxygen-rich blood like every other muscle in the body. When the major arteries to your heart become affected by atherosclerosis, it can lead to coronary artery disease (CAD) or angina. Complications from atherosclerosisĭepending on which artery is blocked, atherosclerosis can cause several health problems. Atherosclerosis doesn’t usually have any symptoms until the artery is blocked by at least half. Mild plaque often doesn’t affect blood flow very much. Atherosclerosis usually starts early in life.
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